Published 2023

Read in Norwegian

Publication details

Journal : Frontiers in Physiology , vol. 14 , p. 1–17 , 2023

Publisher : Frontiers Media S.A.

International Standard Numbers :
Printed : 1664-042X
Electronic : 1664-042X

Publication type : Academic article

Contributors : Pejšková, Lucie; Rønning, Sissel; Kent, Matthew Peter; Solberg, Nina; Høst, Vibeke; To, Thu-Hien; Wold, Jens Petter; Lunde, Marianne; Mosleth, Ellen F.; Pisconti, Addolorata; Kolset, Svein Olav; Carlson, Cathrine Rein; Pedersen, Mona Elisabeth

Research areas

Quality and measurement methods

If you have questions about the publication, you may contact Nofima’s Chief Librarian.

Kjetil Aune
Chief Librarian


The skeletal muscle deformity of commercial chickens (Gallus gallus), known as the wooden breast (WB), is associated with fibrotic myopathy of unknown etiology. For future breeding strategies and genetic improvements, it is essential to identify the molecular mechanisms underlying the phenotype. The pathophysiological hallmarks of WB include severe skeletal muscle fibrosis, inflammation, myofiber necrosis, and multifocal degeneration of muscle tissue. The transmembrane proteoglycans syndecans have a wide spectrum of biological functions and are master regulators of tissue homeostasis. They are upregulated and shed (cleaved) as a regulatory mechanism during tissue repair and regeneration. During the last decades, it has become clear that the syndecan family also has critical functions in skeletal muscle growth, however, their potential involvement in WB pathogenesis is unknown.


Topics associated with the publication