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TailoTides

Sensor-guided and tailored enzymatic protein hydrolysis and separation technologies

Josipa Matic is the post doc in TailoTides. She is going to analyse the samples from the reactor. Foto: Joe Urrutia, Nofima

The scientists will develop new methods for tailoring bioaktive peptides from poultry by-products and Calanus finmarchicus.

Last update

Read in Norwegian

Start

01. Jun 2021

End

30. Sep 2024

Funded by

The Research Council of Norway

Cooperation

Aquateam COWI AS, Norilia and Zooca

Project Manager(s):

Sileshi Gizachew Wubshet

Other Participants:

Josipa Matić

Results

Tailored Peptides: A Key to Better Health

Chicken leftovers have a positive effect on diabetes and high blood pressure

The major goal for this project is to develop novel combination of enzymatic hydrolysis, separation technologies and sensor technologies for tailored and controlled biomanufacturing of bioactive peptides from poultry by-products and Calanus finmarchicus.

Subgoals

  1. Develop and implement biodiscovery platforms for screening and identification of potent bioactive peptide fractions from poultry by-products and Calanus finmarchicus against selected cardiometabolic diseases.
  2. Develop bioactivity-guided enzymatic protein hydrolysis for tailored biomanufacturing of potent hydrolysates.
  3. Develop separation technologies for refining and up concentration of desired bioactive peptides.
  4. Develop advanced bioanalytical and sensor solutions as process control technologies for optimal production of tailored bioactive peptides

Working process

This figure illustrate the working process in the project

Publications

In vitro gastrointestinal stability and intestinal absorption of ACE-1 and DPP4 inhibitory peptides from poultry by-product hydrolysates

Food & Function, 2024 Academic article

Effect of Calanus finmarchicus Hydrolysate Inclusion on Diet Attractiveness for Whiteleg Shrimp (Litopenaeus vannamei)

Fishes, 2024 Academic article

Membrane Separation of Chicken Byproduct Hydrolysate for Up-Concentration of Bioactive Peptides

Membranes, 2024 Academic article

Low Molecular Weight Peptide Fraction from Poultry Byproduct Hydrolysate Features Dual ACE-1 and DPP4 Inhibition

ACS Food & Science Technology, 2023 Academic article

The role of biospectroscopy and chemometrics as enabling technologies for upcycling of raw materials from the food industry

Analytica Chimica Acta, 2023 Academic article

Calanus finmarchicus as a novel source of health-promoting bioactive peptides: Enzymatic protein hydrolysis, characterization, and in vitro bioactivity

Biocatalysis and Agricultural Biotechnology, 2023 Academic article

Calanus finmarchicus hydrolysate improves growth performance in feeding trial with European sea bass juveniles and increases skeletal muscle growth in cell studies

Scientific Reports, 2023 Academic article

Multivariate correlation of infrared fingerprints and molecular weight distributions with bioactivity of poultry by-product protein hydrolysates

Journal of Functional Foods, 2022 Academic article

Research areas

Bioprocessing

Topics

Bioactivity

Enzymes