SEC2MWD: A MATLAB toolbox for derivation of molecular weight distributions from size exclusion chromatography
Publication details
Journal : SoftwareX , vol. 25 , p. 1–7–6 , 2023
Publisher : Elsevier
International Standard Numbers
:
Printed
:
2352-7110
Electronic
:
2352-7110
Publication type : Academic article
Links
:
ARKIV
:
hdl.handle.net/11250/3109735
DOI
:
doi.org/10.1016/j.softx.2023.1...
Research areas
Quality and measurement methods
If you have questions about the publication, you may contact Nofima’s Chief Librarian.
Kjetil Aune
Chief Librarian
kjetil.aune@nofima.no
Summary
Size exclusion chromatography (SEC) is a type of liquid chromatography used for separating molecules based on their size. The pipeline for converting a raw chromatogram to a molecular weight distribution involves multiple steps and require various parameters to be defined for each step. Commercial software lack transparency in terms of methods and algorithms, and it may be cumbersome to explore effects of different parameter settings. We have therefore developed a MATLAB toolbox that reproduces the main functionality of commercial software in a transparent and flexible manner. The toolbox consists of seven main functions, each representing a step in the calculation pipeline. The modular architecture makes it easy to modify or replace individual steps of the pipeline if necessary.
