Published 2023

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Publication details

Journal : Genomics , vol. 115 , p. 15 , 2023

Publisher : Academic Press

International Standard Numbers :
Printed : 0888-7543
Electronic : 1089-8646

Publication type : Academic article

Contributors : Lazado, Carlo C.; Iversen, Marianne; Johansen, Lill Heidi; Brenne, Hanne Britt; Sundaram, Arvind; Ytteborg, Elisabeth

Issue : 6

Research areas

Farmed fish

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We report the histological and transcriptomic changes in the olfactory organ of Atlantic cod exposed to Francisella noatunensis. Experimental infection was performed at either 12oC or 17oC. Infected fish presented the classic gross pathologies of francisellosis. Nasal morpho-phenotypic parameters were not significantly affected by temperature and infection, except for the number of mucus cells in the 12oC group seven weeks after the challenge. A higher number of genes were altered through time in the group reared at 17oC. At termination, the nasal transcriptome of infected fish in both groups was similar to the control. When both infected groups were compared, 754 DEGs were identified, many of which were involved in signalling, defence, transmembrane and enzymatic processes. In conclusion, the study reveals that elevated temperature could trigger responses in the olfactory organ of Atlantic cod and shape the nasal response to F. noatunensis infection.


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