Gene expression profiles in liver of pigs with extreme high and low levels of androstenone

Published 2008

Publication details

Journal : BMC Veterinary Research , vol. 4 , 2008

International Standard Numbers :
Electronic : 1746-6148

Publication type : Academic article

Contributors : Bendixen, Christian; Berget, Ingunn; Grindflek, Eli; Hedegaard, Jakob; Hornshøj, Henrik; Lien, Sigbjørn; Meuwissen, Theodorus; Moe, Maren

Links :
DOI : doi.org/10.1186/1746-6148-4-29
SAMMENDRAG : http://www.biomedcentral.com/1...
OMTALE : http://www.biomedcentral.com/1...

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Summary

Conclusion: A number of genes and pathways related to metabolism of androstenone in liver were identified, including new candidate genes involved in phase I oxidation metabolism, phase II conjugation metabolism, and regulation of steroid availability. The study is a first step towards a deeper understanding of enzymes and regulators involved in pathways of androstenone metabolism and may ultimately lead to the discovery of markers to reduce boar taint.

Contacts:

Ingunn Berget

Scientist