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Published 2003

Read in Norwegian

Publication details

Journal : World Journal of Microbiology & Biotechnology , vol. 19 , p. 777–782 , 2003

International Standard Numbers :
Printed : 0959-3993
Electronic : 1573-0972

Publication type : Academic article

Contributors : Sandsdalen, Erling; Haug, Tor; Stensvåg, Klara; Styrvold, Olaf B.

If you have questions about the publication, you may contact Nofima’s Chief Librarian.

Kjetil Aune
Chief Librarian


An antibacterial compound was isolated from the brown alga Fucus vesiculosus. Purification consisted of extraction of plant material with 0.05% trifluoroacetic acid, concentration on a C18 cartridge, and reverse-phase high performance liquid chromatography on a C18 semi-preparative column. The isolated compound exhibited antibacterial activity against both the Gram-positive and the Gram-negative bacteria tested. The compound showed no haemolytic effect against human red blood cells. Results obtained by electrospray ionization mass spectrometry indicated that the antibacterial activity was caused by a polyhydroxylated fucophlorethol.