Published 2008

Read in Norwegian

Publication details

Journal : Vaccine , vol. 26 , p. 6791–6799 , 2008

Publisher : Elsevier

International Standard Numbers :
Printed : 0264-410X
Electronic : 1873-2518

Publication type : Academic article

Contributors : Lund, Vera; Arnesen, Jan Arne; Mikkelsen, Helene; Gravningen, Kjersti; Brown, Laura; Schrøder, Merete Bjørgan

Issue : 52

If you have questions about the publication, you may contact Nofima’s Chief Librarian.

Kjetil Aune
Chief Librarian


Atypical furunculosis caused by atypical Aeromonas salmonicida, is an emerging problem in farming of Atlantic cod (Gadus morhua) in Norway, and vaccines are needed. Atypical A. salmonicida comprises a heterogeneous group of bacteria differing in surface antigens such as the A-layer protein and lipopolysaccharides (LPS). Except for one of the experimental oil-adjuvanted whole cell vaccines based on various isolates they all resulted in moderate protection. No clear correlation between vaccine efficacies and the A-protein group or LPS type of the vaccine isolates was revealed, while a correlation between efficacy and the presence of cross-reacting LPS-specific antibodies is indicated.