Atypical furunculosis vaccines for Atlantic cod (Gadus morhua); vaccine efficacy and antibody responses
Publication details
Journal : Vaccine , vol. 26 , p. 6791–6799 , 2008
Publisher : Elsevier
International Standard Numbers
:
Printed
:
0264-410X
Electronic
:
1873-2518
Publication type : Academic article
Issue : 52
Links
:
DOI
:
doi.org/10.1016/j.vaccine.2008...
If you have questions about the publication, you may contact Nofima’s Chief Librarian.
Kjetil Aune
Chief Librarian
kjetil.aune@nofima.no
Summary
Atypical furunculosis caused by atypical Aeromonas salmonicida, is an emerging problem in farming of Atlantic cod (Gadus morhua) in Norway, and vaccines are needed. Atypical A. salmonicida comprises a heterogeneous group of bacteria differing in surface antigens such as the A-layer protein and lipopolysaccharides (LPS). Except for one of the experimental oil-adjuvanted whole cell vaccines based on various isolates they all resulted in moderate protection. No clear correlation between vaccine efficacies and the A-protein group or LPS type of the vaccine isolates was revealed, while a correlation between efficacy and the presence of cross-reacting LPS-specific antibodies is indicated.
