Publisher : Nofima AS
International Standard Numbers
Printed : 978-82-8296-698-6
Publication type : Nofima’s reports
Series : Nofima rapportserie 35/2021
Year : 2021
If you have questions about the publication, you may contact Nofima’s Chief Librarian.
The project addressed a new type of vertebral deformities in Atlantic salmon, called “cross-stitch” vertebrae. Analysis of production data showed that vaccine was a major risk factor, and that 0+ smolts were more affected than 1+. On histology, a ring-formed defect in vertebral endplates was found in vertebrae with typical lesions, located close to vertebral centra. The link to vaccination was confirmed in a long-term fish experiment, and typical lesions were found in fish groups vaccinated with oil-adjuvanted vaccines which included a PD-component. Initial in vitro studies indicated that cell culture may be a useful future approach to this problem.